Over in the Premier League, the scrappy West Ham united stunned Liverpool, the only unbeaten team in the league, with the Klopp boys losing a streak that dated back to April, thanks to a superb performance by Kurt Zouma.
Ligue 1 giants Paris Saint-Germain had to rely on old-faithful Neymar, who scored a brace to secure a hard-fought victory against Bordeaux 3-2, which helps them maintain a 10-point lead in France.
Heading back to England for the Manchester derby, it was all City asserting dominance over United, with a comfortable 2-0 victory thanks to Bernando Silva's scintillating display, culminating with a wonder goal to secure the three points.
FIFA 22 Team of the Week 8 - predictions
We have split our predictions between the starting XI and bench
Players will be available from Wednesday at 6 pm BST and in packs for seven days after the fact.
- GK: Jonas Omlin (Montpellier)
- RB: Hamari Traoré (Stade Rennais)
- CB: Kurt Zouma (West Ham)
- CB: Mattia Caldara (FC Venezia)
- LB: Adrià Pedrosa (Espanyol)
- CM: Toni Kroos (Real Madrid)
- CM: Cristopher Nkunku (RB Leipzig)
- LW: Neymar (PSG)
- AM: Leon Goretzka (Bayern Munich)
- RW: Bernardo Silva (Manchester City)
- CF: R. Santos Borré (Eintracht Frankfurt)
- GK: Ben Foster (Watford)
- CB: Artyom Mamin (FC Ural)
- CB: Michael Keane (Everton)
- CB: Gonçalo Inácio (Sporting CP)
- CM: Mikel Merino (Real Sociedad)
- CM: Manu Trigueros (Villarreal)
- LM: Luis Díaz (Porto)
- RM: João Pedro (Tondela)
- AM: Vyacheslav Grulyov (Dynamo Moscow)
- ST: Ciro Immobile (Lazio)
- ST: Aleksandar Mitrovic (Fulham)
- ST: Cristhian Stuani (Gironia)
FIFA 22 TOTW 8 players will be available from Wednesday, 10th November (6 pm UK) and will be in FUT packs for seven days.
We'll keep you up to date with all the other important news and storylines surrounding FIFA 22 over on our dedicated page.
Featured image courtesy of EA Sports.