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Cyberpunk 2077: how to “one-hit kill” opponents with launcher/tranquillizer combo

YouTuber and Cyberpunk 2077 player, ESO, discovered this overpowered set up that basically one-hit kills enemies of any difficulty.
Cyberpunk 2077: how to “one-hit kill” opponents with launcher/tranquillizer combo

Now that Cyberpunk 2077 is in your hands, new strats and metas have been found less than a week after release. One of them, found by YouTuber ESO, might be one that breaks the game entirely.

This combo, in turn, ruins the experience just because of how powerful it is, so use at your own discretion. Regardless, here is how to “one-hit kill” enemies and bosses alike in Cyberpunk 2077.

How to one-hit kill in Cyberpunk 2077

For this combo, you are going to need two things: a Projectile Missile Launcher and Tranquillizer Darts.

(Picture: CD Projekt Red)

To get Tranquillizer Darts, head out to Heywood, just south of City Center. Near the coast, you will be able to find a Ripperdoc. Your fastest route will be to use the Fast Travel point right next to it.

(Picture: CD Projekt Red)

Crossing the streets and walking up the stairs will bring you in front of the Ripperdoc who you have to talk with to buy Tranquillizer Darts. Now, this isn’t the only way to get them, but it is definitely the quickest way to do so.

Once in the Ripperdoc menu, go to the Trade tab and you will see the Tranquillizer Rounds for sale, priced at 540 Eddies. The description reads: “Non-Lethal. Enemies shot with this type of round will lose consciousness.”  (Picture: CD Projekt Red)

You can also get different Projectile Launch Systems in the game, but the fast and easy version is to go Watson, north of City Center. Go to the Fast Travel point in Little China, cross the street and go through the doorway with the neon word “POD” with Hanzi letters around it.

(Picture: CD Projekt Red)

Follow the pathway down the stairs and go into Viktor’s shop to talk to him. You can bring your own or buy the Projectile Launch System from Viktor for around 21,000 Eddies. 

The Projectile Launch System needs to be installed in your body by a Ripdoctor, so you might as well get the system from Viktor, then head to Heywood to buy your darts as you get it installed.

After installation, you’ll need to set up the combo in your menu. First,  head to your Inventory and make sure your Projectile Launch System is in place of your grenades. You can always switch back if you feel the need to.

Then, go to Cyberware and select your Arms where you can change your projectiles to be the Tranquillizer Rounds instead of the default explosives and voila! 

You are ready to one-shot kill minions, psycho-cyborgs and bosses.

(Picture: CD Projekt Red)

This combo is effective as Tranquillizer Darts do not have a timer value set in place, so no matter the level of difficulty or rank of the enemy, they will be left on the ground unconscious forever.

Although it is pretty fun at first, it definitely takes out the fun of grinding and levelling up through your own. It wouldn’t surprise us that CD Projekt Red got behind this OP set up, and tweaked it a notch as to make it functional without breaking the game.

If you want to see just how powerful this strat really is, check out ESO’s video on the matter on his YouTube channel or in the link down below: