Dead Rails Potion Tier List (2025) - Best Potions Ranked

Dead Rails just got a whole lot messier with the arrival of potions. While some are basically liquid gold, others are better off dumped straight into the void. But how do you know which brew to bet your Unicorn Blood on? Well, that's where my Dead Rails tier list comes in.

I’m breaking down every potion in the game, from undead-summoning powerhouses to utterly useless flops to help you turn the tide of battle. When you're done, be sure to read my class tier list for even more great tips!

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What Is The Best Potion In Dead Rails? | Roblox

Primordial Soup is the best potion in Dead Rails because it turns corpses into allies, effectively summoning an undead army that fights for you. It doesn’t require a special class, is easy to craft with milk and unicorn blood, and can solo-clear endgame zones if you prepare a large pile of bodies.

Angel Tears is the second-best because it grants passive healing over time. While it's not as explosive as Primordial Soup, it’s valuable in tough modes like Nightmare, especially when used preemptively. It lasts longer than snake oil and keeps you alive mid-fight in Dead Rails.

Dead Rails Tier List: Every Potion Ranked | Roblox

There are only four potions in Dead Rails, not including Milk and Kerosene. I've ranked each of them below so you know exactly which ones are worth brewing. Some concoctions really aren't worth the Unicorn Blood spent crafting them, while others pack quite a punch!

Editor's Comment: Please note that this tier list is based on the author's opinions. As such, these rankings might differ wildly based on your personal play style, skill level, and preference. If you're not convinced by these ratings, message me with your opinions.

Did I make a mistake? Please let me know by emailing me at [email protected] so I can fix it. Thank you!

And that concludes my Dead Rails potion tier list. Don't forget to check out some of my other Roblox guides — Bladers: Rebirth, Death Ball, Jujutsu Chronicles, Anime Champions Simulator, Haze Piece, Peroxide, TYPE SOUL, Anime Fighters, Project Slayers, Roblox King Legacy, Murder Mystery 2, Adopt Me, Love Nikki, Anime Dimensions, Shindo Life, All-Star Tower Defense, or Skibi Toilet Tower Defense.