If you're here, there's a good chance you want to know how to clear the Vyeresz Stronghold in Diablo 4. Did we guess right? Go figure. That said, you shouldn't be embarrassed by being here. Each Stronghold in Sanctuary is challenging, boasting formidable foes and lucrative rewards. So, it's only a matter of time before you'll need help to clear them.
Much like the Crusaders' Monument, the Vyeresz Stronghold in Diablo 4 is located in Hawezar and is home to a dangerous boss named Dianthus. But don't worry. This guide details everything about the Vyeresz Stronghold in Diablo 4, including its location, how to clear it, and the rewards after beating it.
Editor's note: Having a good time exploring Sanctuary? Pfft... of course you are! What kind of question is that?! We hope you find our guides useful. If not, please let us know. While I still have your attention, check out our Diablo 4 review!
Table of Contents
Diablo 4: Vyeresz Stronghold Location Hawezar Region

Located in the southern region of Hawezar, just north of the Toxic Fens, you will discover the Vyeresz Stronghold in Diablo 4. To initiate your search for the Stronghold, a recommended starting point is the Ruins of Rakhat Keep. From there, head south into the Fethis Wetlands and continue in a southerly direction.
Vyeresz is a village in southern Hawezar, which has fallen under the control of cultists who worship a deity referred to as the "Serpent God." Inside the town, you will encounter various serpent-like creatures and the human cultists who venerate them.
Battle your way toward the village's center, where you will come across a structure featuring an elaborate, sizeable door adorned with a glyph encompassed by three Serpent eyes. This door, known as the Serpent's Eye Door, is the starting point for the Vyeresz Stronghold.
Diablo 4: How To Conquer Vyeresz Stronghold

To open the Serpent's door and proceed to clear the Vyeresz Stronghold in Diablo 4, players need to find and destroy three Serpent's Eye Pedestals that correspond to the door to unlock it. These are scattered around the Stronghold, some of which are more heavily guarded than others.
The initial pedestal can be located outside the structure, surrounded by petrified cultists. To destroy it, click on the pedestal. Another pedestal awaits in a large hut northwest of the Serpent's Eye Door, guarded by Rikrad, an elite cultist, and his companions.
Overcome these adversaries and demolish the Serpent's Eye. Moving east of the door, you will discover another substantial hut with the final Serpent's Eye on the right side. Eliminate Vescir, the elite cultist, and the lesser foes protecting the pedestal.

Once all three Serpent's Eyes have been dealt with, return to the Serpent's Eye Door and interact with it. Now, you must survive for 50 seconds while facing a horde of cultists as the door opens. Initially, the waves of cultists will be slow, but they will gradually increase in number as the countdown progresses.
The petrified cultists near the first pedestal will break free and join the assault. Swiftly eliminate all opponents. They should not pose a significant threat as long as you consistently dispatch them before their numbers become overwhelming. But stay vigilant because several Nagari Longfang elites will burst through when the door opens.
Proceed through the path behind the door, following the southeast route. Keep following this path until you discover the Altar of Lilith, which you can claim. Once prepared, return to the original path and make your way towards the Healing Well located in the center, your last resting stop before encountering the boss of the Vyeresz Stronghold: Dianthus.
Diablo 4: How To Beat Dianthus In Vyeresz Stronghold

Dianthus, the boss in the form of a serpent-like Nangari Longclaw, possesses several special attacks. Upon spawning, Dianthus will launch forward with its massive fangs, stunning players upon a successful hit. This ability is utilized periodically throughout the fight but can be easily anticipated as the boss winds up slowly before executing the attack.
Another move is an AoE (Area of Effect) attack where Dianthus creates a large-radius ripple that expands. After a brief delay, the ripple explodes, inflicting significant poison damage. To avoid this, swiftly move out of the area of effect as soon as you notice it.
Dianthus occasionally releases two fans of projectiles around itself, but these projectiles cause minimal damage. The boss may raise its arms and launch several projectiles toward the ground, resulting in lingering blood pools. While these pools are relatively easy to evade, they deal substantial damage if you happen to get caught in them.
Alongside these attacks, Serpent adds will periodically spawn during the fight, attacking from a distance. Therefore, it is advisable to eliminate them when possible to mitigate their damage. So, stay close to the boss, try to avoid its main attacks while dealing damage, and steer clear of the AoE attack until the boss falls.

Diablo 4: Vyeresz Stronghold Rewards
With Danthius defeated and the Vyeresz Stronghold cleared, let's discuss the valuables you'll gain as a reward for doing so. The first is the default reward for clearing a Stronghold in the game, Renown. Usually, you'd get 100 Renown for clearing a Stronghold, but Vyeresz grants players 120 Renown, making it worthwhile to clear.
Vyeresz is also one of the rare Strongholds that transform into a player-friendly settlement once cleared, complete with its own Waypoint, vendors, and grants access to new Side Quests. You'll also unlock the Shadowed Plunge dungeon northeast of the Stronghold, ripe with its rewards if you venture inside.
During your journey through the Stronghold, you are guaranteed to encounter rare drops, with a chance of obtaining legendary items, although they may be less common than rare drops. Alongside these valuable items, you will also accumulate a significant amount of experience and gold. Lastly, it is worth noting that the items dropped within Strongholds have power levels approximately two levels higher than your character's level.
And that concludes our guide on how to clear the Vyeresz Stronghold Stronghold in the Hawezar region of Diablo 4. We recommended clearing this Stronghold as soon as possible to acquire the resources to be found there and unlock the Waypoint located here and turn Vyeresz into a base of operations in Diablo 4's Hawezar region.
Diablo 4 Vyeresz Stronghold: How To Beat, Location & Rewards FAQ
Where is the Vyeresz Stronghold located in Diablo 4?
The Vyeresz Stronghold is located in the southern region of Hawezar, just north of the Toxic Fens.
How do I clear the Vyeresz Stronghold in Diablo 4?
To clear the Vyeresz Stronghold, you need to destroy three Serpent's Eye Pedestals, unlock the Serpent's Eye Door, survive the cultist assault, and defeat the boss, Dianthus.
What are the rewards for clearing the Vyeresz Stronghold in Diablo 4?
Clearing the Vyeresz Stronghold grants 120 Renown, transforms it into a player-friendly settlement with its own Waypoint and vendors, unlocks new Side Quests, and grants access to the Shadowed Plunge dungeon. You can also expect rare drops, legendary items, experience, gold, and higher-level items as rewards.
For more Diablo 4, be sure to check out our dedicated section or some of our Guides & Tutorials just below:
Diablo 4 Class Builds - Best Barbarian Build | | Best Necromancer Build | Best Sorcerer Build | Best Druid Build | Best Rogue Build | All Classes Tier List | Best Class For Beginners | Build Calculator |
Class Mechanics: Sorcerer Enchantment System | Barbarian Arsenal | Rogue Specialization | Necromancer Book of the Dead | Druid Spirit Animals | Unlock Golems |
Items - Healing Vial | Item Slot Types | Transmogs/Wardrobe | Salvage Items | Durability & Repair | Trading Items | All Unique Items & Stats | Set Items | Item Quality/Rarity Levels | Elixirs | Butcher's Cleaver | Cry of Ashava Trophy |
Features: Beginners Guide | Impressions From Beta |
Quests: Ritual Tower Key | Forgive Me Side Quest | Traveler's Prayer Side Quest | Secret Of The Spring Riddle | Raising Spirits Side Quest | Woodsman Of Nevesk | Fiend Rose |
General D4 Guides: Legendary & Gold Farming | Town Portal | Inventory Size | Stash Size | Beat Lilith's Lament | Beat Den Mother Boss | Beat Lord Avitus Boss | Beat Blood Bishop Boss | Reset Dungeons | Gathering Legions Guide | The Butcher Boss | Leave Dungeons | All Stronghold Locations | Hardcore Mode | Change Difficulty | Unlock/Launch Time | Balance Changes | Patch Notes |
Diablo 4 Tech Guides - Ray Tracing Support | Couch Co-Op | Server Regions | PC Requirements & File Size | Diablo 4 Servers Down? | Connection Issues Fix | Crashing Issues Fix | Unable To Install or Patch | Low FPS Fix | Error Code 34202 Fix | Disable Fog & Glare | Stuck in Queue Fix | Console Issues | PC Issues | Enable & Disable Chat Bubbles | Hit Max Level Fast | Best PC Settings High FPS | Error Code 395002 Fix | Error Code 316719 Fix | D4 on Steam Deck | Offline Mode | DLSS 3 & NVIDIA Reflex |
Crafting/Vendors - Jeweler | Gambling & Obols | Occultist | Alchemist | Blacksmith | | Monster Parts | Skins | Ore | Plants |
Legendary Aspects - Codex of Power | Sorcerer Legendary Powers | Barbarian Legendary Powers | Rogue Legendary Powers | Necromancer Legendary Powers | Druid Legendary Powers
Activities - Strongholds | Nightmare Dungeons | Silent Chests | Altars of Lilith | Helltides | Endgame |
Story & Lore - Campaign Length | Who is Lilith? | Who is Inarius | Deckard Cain | Secret Cow Level | All D4 Acts Listed |
Zones - Fractured Peaks Overview | Scosglen | Kehjistan | Dry Steppes | Hawezar | All Waypoint Locations | Full World Map | Fractured Peaks Chests | Fractured Peaks Cellars |
Stronghold Guides - Kor Dragan | Malnok | Nostrava |
Mounts - Temptation Mount | Diablo 4 Class Dismount Mechanics | Unlock & Customize |
Seasons - Battle Pass Price | Diablo 4 Season Duration | Battle Pass Differences | Get Favor | Next Season Start Date | Season Blessings | Season Journey | Diablo 4 Content Roadmap |
Gameplay Systems - Armor System | Clans | Primary Stats & Effects | Shrines & Buffs | Renown & Reputation | Max Level & Paragon Cap | World Tier Difficulty Levels | Followers/Mercenaries |
World Bosses - Ashava | Avarice | Wandering Death | Beat Ashava | Ashava Spawn Location |
Diablo 4 Misc - Statue of Inarius Price & Specs | Wolf Pack Cosmetic | Codes | Diablo 4 Free-to-Play? | Mother's Inked Title | Collector's Edition | How To Respec | Stagger Mechanic | Patch Notes | Asmongold Diablo 4 Beta Thoughts | Item Shop | Wings of the Creator Emote |
Challenges/Achievements - Necromancer Challenges | Barbarian Challenges | Druid Challenges | Rogue Challenges | Sorcerer Challenges | Crafting Challenges
Diablo 4 PvP - Coming soon!
Our section keeps growing, so check for new guides daily! Don't forget to pick up one of the Diablo 4 Editions and join the fight to save Sanctuary soon.